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KMID : 0032220210330020182
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Annals of Dermatology
2021 Volume.33 No. 2 p.182 ~ p.185
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Cryosurgery as a Minimally Invasive Alternative Treatment for a Patient with Erosive Adenomatosis of the Nipple
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Bae Kyung-Nam
Shin Ki-Hyuk
Kim Woo-Il
Yang Min-Young
Lee Won-Ku
Kim Hoon-Soo
Ko Hyun-Chang
Kim Byung-Soo
Kim Moon-Bum
Kim Gun-Wook
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Abstract
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Erosive adenomatosis of the nipple (EAN), also known as nipple adenoma, florid papillomatosis, or papillary adenoma of the nipple, is a benign neoplasm originating from a lactiferous duct of the breast. Although the potential for malignant change is invariably negligible, the nature of the disease is quite intractable despite several treatment methods. Surgical excision is known as the treatment of choice, but this invasive approach is generally not acceptable to the vast majority of patients due to the cosmetic outcomes. Cryosurgery could be an alternative choice to preserve the structure of the nipple-areola complex, though its application has not been studied due to the paucity of cases. A 22-year-old female presented with a unilateral, crater-like erosion of the left nipple with serosanguineous discharge. The skin biopsy revealed proliferation of tubular structures, which corresponded to EAN. She was treated with 4 sessions of cryosurgery (open cryospray with liquid nitrogen) over 6 months, and the skin lesion resolved completely without any recurrence for 12 months. Although further study is required to determine the optimal treatment regimen for EAN, cryosurgery should be considered as an effective option to surgical excision.
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KEYWORD
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Apocrine glands, Cryosurgery, Erosive adenomatosis of the nipple
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